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The length of the AR CAG repeat polymorphism was positively related to traits of hypogonadism.


All XX males were infertile and most were hypogonadal.

They found accelerated growth in early childhood in boys with 47, XXY and 47, XYY karyotypes, whereas 46, XX males were shorter than controls.

These abnormal growth patterns were not reflected in circulating levels of IGF1 and IGFBP3.

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